NEWS

2021.10.06

REASERCH

Our new paper is out in Blood!

IgH-CRLF2-rearranged B-ALL (acute lymphoblastic leukemia) is a disease subtype that dictates poor clinical outcome. Using CRISPR/Cas9-screen/mutagenesis scan, we delineate molecules/pathways relevant for IgH-CRLF2-r ALL pathogenesis and suggest rationally designed combination therapies appropriate for the disease subtype. This study was led by Dr. Kensuke Sasaki and published in Blood (https://ashpublications.org/blood/article/doi/10.1182/blood.2021012976/477079).